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1

Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

Yamada, Naoya, Karasawa, Tadayoshi, Kimura, Hiroaki, Watanabe, Sachiko, Komada, Takanori, Kamata, Ryo, Sampilvanjil, Ariunaa, Ito, Junya, Nakagawa, Kiyotaka, Kuwata, Hiroshi, Hara, Shuntaro, Mizuta, K

Journal:

Cell Death and Disease

Year:

2020

Language:

english

File:

PDF, 3.59 MB

english, 2020

2

Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis

Sasaki, Yuka, Nakatani, Yoshihito, Hara, Shuntaro

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2015

Language:

english

File:

PDF, 683 KB

english, 2015

3

Deep and superficial circumflex iliac arteries and their relationship to the ultrasound-guided femoral nerve block procedure: A cadaver study

Ogami, Keiko, Murata, Hiroaki, Sakai, Akiko, Sato, Shuntaro, Saiki, Kazunobu, Okamoto, Keishi, Manabe, Yoshitaka, Hara, Tetsuya, Tsurumoto, Toshiyuki

Journal:

Clinical Anatomy

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

4

Clinical Efficacy of Bone Reconstruction Surgery with Frozen Cortical Bone Allografts for Nonunion of Radial and Ulnar Fractures in Toy Breed Dogs

Munakata, Shuntaro, Nagahiro, Yukari, Katori, Daichi, Muroi, Norihiro, Akagi, Hiroyuki, Kanno, Nobuo, Harada, Yasuji, Yamaguchi, Shinya, Hayashi, Kei, Hara, Yasushi

Journal:

Veterinary and Comparative Orthopaedics and Traumatology

Year:

2018

Language:

english

File:

PDF, 550 KB

english, 2018

5

Association between clinical symptoms and postâmortem neuropathology in dementia with Lewy bodies

Kaneko, Yoshitsugu, Hirao, Kentaro, Serisawa, Shuntaro, Kanetaka, Hidekazu, Shimizu, Soichiro, Hirai, Hideaki, ShishidoâHara, Yukiko, Umahara, Takahiko, Sakurai, Hirofumi, Hanyu, Haruo

Journal:

Geriatrics & Gerontology International

Year:

2020

File:

PDF, 512 KB

2020

6

Overexpression of thioredoxin reductase 1 regulates NF-κB activation

Atsuko Sakurai, Kouji Yuasa, Yasuko Shoji, Seiichiro Himeno, Masafumi Tsujimoto, Manabu Kunimoto, Nobumasa Imura, Shuntaro Hara

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 315 KB

english, 2004

7

Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: Role of NF-E2-related factor-2

Atsuko Sakurai, Michie Nishimoto, Seiichiro Himeno, Nobumasa Imura, Masafumi Tsujimoto, Manabu Kunimoto, Shuntaro Hara

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 358 KB

english, 2005

8

Selective disappearance of an axonal protein, 440-kDa ankyrinB, associated with neuronal degeneration induced by methylmercury

Motoharu Sakaue, Hiromi Takanaga, Tatsumi Adachi, Shuntaro Hara, Manabu Kunimoto

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 887 KB

english, 2003

9

Involvement of independent mechanism upon poly(ADP-ribose) polymerase (PARP) activation in methylmercury cytotoxicity in rat cerebellar granule cell culture

Motoharu Sakaue, Naoko Mori, Maiko Okazaki, Mayuka Ishii, Yayoi Inagaki, Yuka Iino, Kiyomi Miyahara, Mai Yamamoto, Takeshi Kumagai, Shuntaro Hara, Masako Yamamoto, Kazuyoshi Arishima

Journal:

Journal of Neuroscience Research

Year:

2008

Language:

english

File:

PDF, 431 KB

english, 2008

10

Vitamin K has the potential to protect neurons from methylmercury-induced cell death In Vitro

Motoharu Sakaue, Naoko Mori, Maiko Okazaki, Erika Kadowaki, Takuya Kaneko, Natsuko Hemmi, Hitomi Sekiguchi, Takehiro Maki, Aisa Ozawa, Shuntaro Hara, Kazuyoshi Arishima, Masako Yamamoto

Journal:

Journal of Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 407 KB

english, 2011

11

Pathological roles of microsomal prostaglandin E synthase-1 (mPGES-1) in Alzheimer's disease

Shuntaro Hara, Yukiko Kuroki

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 67 KB

english, 2009

12

Microsomal prostaglandin E synthase-1 (mPGES-1) deficiency suppresses chemical carcinogen-induced colon carcinogenesis

Yuka Sasaki, Daisuke Kamei, Yukio Ishikawa, Toshiharu Ishii, Shuntaro Hara

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 212 KB

english, 2009

13

Involvement of calcium-independent phospholipase A2γ in adipose differentiation

Emiko Yoda, Shuntaro Hara

Journal:

Chemistry and Physics of Lipids

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

14

Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors

Masayasu Urushibara, Junichiro Ishioka, Nobuhiko Hyochi, Kazunori Kihara, Shuntaro Hara, Pratap Singh, John T. Isaacs, Yukio Kageyama

Journal:

Year:

2007

Language:

english

File:

PDF, 227 KB

english, 2007

15

Acceleration of narrow band method and its application to topology-adaptive 3D geometrical modeling

Shuntaro Yui, Kenji Hara, Hongbin Zha, Tsutomu Hasegawa

Journal:

Systems and Computers in Japan

Year:

2006

Language:

english

File:

PDF, 1.84 MB

english, 2006

16

Skeletal muscle weakness and atrophy in membrane-associated calcium-independent phospholipase A2 (iPLA2γ)-deficient mice

Emiko Yoda, Makoto Murakami, Ichiro Kudo, Shuntaro Hara

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 58 KB

english, 2009

17

Very low levels of methylmercury induce cell death of cultured rat cerebellar neurons via calpain activation

Motoharu Sakaue, Maiko Okazaki, Shuntaro Hara

Journal:

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

18

In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

Hiroshi Nagai, Tatsuya Horikawa, Isao Hara, Atsushi Fukunaga, Shuntaro Oniki, Masahiro Oka, Chikako Nishigori, Masamitsu Ichihashi

Journal:

Experimental Dermatology

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

19

Suppression of mutant androgen receptors by flutamide

Junichiro Ishioka, Shuntaro Hara, John T Isaacs, Arihiro Tomura, Kiyohiro Nishikawa, Yukio Kageyama

Journal:

International Journal of Urology

Year:

2009

Language:

english

File:

PDF, 263 KB

english, 2009

20

Effect of the hsp90 inhibitor geldanamycin on androgen response of prostate cancer under hypoxic conditions

Yasutomo Suzuki, Yukihiro Kondo, Shuntaro Hara, Ryouji Kimata, Taiji Nishimura

Journal:

International Journal of Urology

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

21

β-Naphthoflavone disturbs astrocytic differentiation of C6 glioma cells by inhibiting autocrine interleukin-6

Hiromi Takanaga, Tomoko Yoshitake, Emi Yatabe, Shuntaro Hara, Manabu Kunimoto

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

22

Hypoxia downregulates farnesoid X receptor via a hypoxia-inducible factor-independent but p38 mitogen-activated protein kinase-dependent pathway

Tomofumi Fujino, Kaori Murakami, Issei Ozawa, Yoshie Minegishi, Ryo Kashimura, Toshihiro Akita, Susumu Saitou, Takehisa Atsumi, Takashi Sato, Ken Ando, Shuntaro Hara, Kiyomi Kikugawa, Makio Hayakawa

Journal:

Year:

2009

Language:

english

File:

PDF, 472 KB

english, 2009

23

Acceleration of methylmercury-induced cell death of rat cerebellar neurons by brain-derived neurotrophic factor in vitro

Motoharu Sakaue, Naoko Mori, Misato Makita, Kana Fujishima, Shuntaro Hara, Kazuyoshi Arishima, Masako Yamamoto

Journal:

Year:

2009

Language:

english

File:

PDF, 977 KB

english, 2009

24

Involvement of the constitutive prostaglandin E synthase cPGES/p23 in expression of an initial prostaglandin E2 inactivating enzyme, 15-PGDH

Yoshihito Nakatani, Yutaka Hokonohara, Yusuke Tajima, Ichiro Kudo, Shuntaro Hara

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

25

Modulation of telomerase activity by zinc in human prostatic and renal cancer cells

Kaoru Nemoto, Yukihiro Kondo, Seiichiro Himeno, Yasutomo Suzuki, Shuntaro Hara, Masao Akimoto, Nobumasa Imura

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 321 KB

english, 2000

26

Molecular cloning of cDNAs encoding hypoxia-inducible factor (HIF)-1α and -2α of bovine arterial endothelial cells

Shuntaro Hara, Chie Kobayashi, Nobumasa Imura

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1999

Language:

english

File:

PDF, 1021 KB

english, 1999

27

Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2

Tetsuya KOSAKA, Atsuro MIYATA, Hayato IHARA, Shuntaro HARA, Tamiko SUGIMOTO, Osamu TAKEDA, Ei-ichi TAKAHASHI, Tadashi TANABE

Journal:

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

28

Expression and Characterization of Hypoxia-Inducible Factor (HIF)-3α in Human Kidney: Suppression of HIF-Mediated Gene Expression by HIF-3α

Shuntaro Hara, Junko Hamada, Chie Kobayashi, Yukihiro Kondo, Nobumasa Imura

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 320 KB

english, 2001

29

Human Gene Encoding Prostacyclin Synthase (PTGIS): Genomic Organization, Chromosomal Localization, and Promoter Activity

Chieko Yokoyama, Tomoko Yabuki, Hiroyasu Inoue, Yoshinori Tone, Shuntaro Hara, Toshihisa Hatae, Masami Nagata, Ei-Ichi Takahashi, Tadashi Tanabe

Journal:

Year:

1996

Language:

english

File:

PDF, 313 KB

english, 1996

30

Nuclear Localization of Hypoxia-Inducible Factor-2α in Bovine Arterial Endothelial Cells

Shuntaro Hara, Chie Kobayashi, Nobumasa Imura

Journal:

Molecular Cell Biology Research Communications

Year:

1999

Language:

english

File:

PDF, 251 KB

english, 1999

31

Mammalian non-pancreatic phospholipases A2

Ichiro Kudo, Makoto Murakami, Shuntaro Hara, Keizo Inoue

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1993

Language:

english

File:

PDF, 2.06 MB

english, 1993

32

Detection and purification of two 14 kDa phospholipase A2 isoforms in rat kidney: their role in eicosanoid synthesis

Shuntaro Hara, Ichiro Kudo, Takeshi Komatani, Katsuhiko Takahashi, Yoshihito Nakatani, Yasuhiro Natori, Mieko Ohshima, Keizo Inoue

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 620 KB

english, 1995

33

Monoclonal antibodies against human synovial phospholipase A2

Kiyoshi Takayama, Ichiro Kudo, Shuntaro Hara, Makoto Murakami, Kunio Matsuta, Terumasa Miyamoto, Keizo Inoue

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 678 KB

english, 1990

34

Detection of 14-kDa group II phospholipase A2 in human seminal plasma

Kiyoshi Takayama, Shuntaro Hara, Ichiro Kudo, Keizo Inoue

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 679 KB

english, 1991

35

The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells

Hiroyasu Inoue, Toyomichi Nanayama, Shuntaro Hara, Chieko Yokoyama, Tadashi Tanabe

Journal:

Year:

1994

Language:

english

File:

PDF, 797 KB

english, 1994

36

Abundant expression of thromboxane synthase in rat macrophages

Yoshinori Tone, Atsuro Miyata, Shuntaro Hara, Susumu Yukawa, Tadashi Tanabe

Journal:

Year:

1994

Language:

english

File:

PDF, 469 KB

english, 1994

37

Site-directed mutagenesis of human prostacyclin synthase: Alteration of Cys441 of the Cys-pocket, and Glu347 and Arg350 of the EXXR motif

Toshihisa Hatae, Shuntaro Hara, Chieko Yokoyama, Tomoko Yabuki, Hiroyasu Inoue, Volker Ullrich, Ta-i Tanabe

Journal:

Year:

1996

Language:

english

File:

PDF, 696 KB

english, 1996

38

Differential contributions of protein kinase C isoforms in the regulation of group IIA secreted phospholipase A2 expression in cytokine-stimulated rat fibroblasts

Mizuki Sugita, Hiroshi Kuwata, Ichiro Kudo, Shuntaro Hara

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 331 KB

english, 2010

39

Subcellular localization and regulation of hypoxia-inducible factor-2α in vascular endothelial cells

Ryo Takahashi, Chie Kobayashi, Yukihiro Kondo, Yoshihito Nakatani, Ichiro Kudo, Manabu Kunimoto, Nobumasa Imura, Shuntaro Hara

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 609 KB

english, 2004

40

Immediate prostaglandin E2 synthesis in rat 3Y1 fibroblasts following vasopressin V1a receptor stimulation

Yoshihito Nakatani, Yuka Chin, Shuntaro Hara, Ichiro Kudo

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 166 KB

english, 2007

41

Deletion of microsomal prostaglandin E synthase-1 protects neuronal cells from cytotoxic effects of β-amyloid peptide fragment 31–35

Yukiko Kuroki, Yuka Sasaki, Daisuke Kamei, Yoshiharu Akitake, Mitsuo Takahashi, Satoshi Uematsu, Shizuo Akira, Yoshihito Nakatani, Ichiro Kudo, Shuntaro Hara

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 495 KB

english, 2012

42

Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models

Shuntaro Hara, Daisuke Kamei, Yuka Sasaki, Akemi Tanemoto, Yoshihito Nakatani, Makoto Murakami

Journal:

Year:

2010

Language:

english

File:

PDF, 669 KB

english, 2010

43

Enhanced antitumor activity of xanthohumol, a diacylglycerol acyltransferase inhibitor, under hypoxia

Keiko Goto, Tomohiro Asai, Shuntaro Hara, Ichiji Namatame, Hiroshi Tomoda, Mamoru Ikemoto, Naoto Oku

Journal:

Year:

2005

Language:

english

File:

PDF, 233 KB

english, 2005

44

Regulatory role of metallothionein in NF-κB activation

Atsuko Sakurai, Shuntaro Hara, Noriko Okano, Yukihiro Kondo, Jun-ichiro Inoue, Nobumasa Imura

Journal:

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

45

Left ventricular geometry as an independent predictor for extracardiac target organ damage in essential hypertension

Yuji Shigematsu, Mareomi Hamada, Tomoaki Ohtsuka, Hidetoshi Hashida, Shuntaro Ikeda, Taishi Kuwahara, Yuji Hara, Koji Kodama, Kunio Hiwada

Journal:

American Journal of Hypertension

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

46

Coronary blood flow in hypertensive patients with heart failure

Mareomi Hamada, Taishi Kuwahara, Go Hiasa, Tomoaki Ohtsuka, Shuntaro Ikeda, Hidetoshi Hashida, Shigeki Uemura, Makoto Suzuki, Yuji Hara, Yuji Shigematsu, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

47

The beneficial effect of beta blockade on cytokine levels in patients with dilated cardiomyopathy

Tomoaki Ohtsuka, Mareomi Hamada, Akiyoshi Ogimoto, Go Hiasa, Osamu Sasaki, Shuntaro Ikeda, Makoto Suzuki, Yuji Hara, Yuji Shigematsu, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

48

Relationship between coronary blood flow and left ventricular function in essential hypertension

Osamu Sasaki, Mareomi Hamada, Yuji Shigematsu, Yuji Hara, Makoto Suzuki, Shuntaro Ikeda, Tomoaki Ohtsuka, Go Hiasa, Akiyoshi Ogimoto, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 140 KB

english, 1999

49

Left ventricular geometric patterns and altered force-frequency relations in isolated myocytes from dahl salt-sensitive rats during cardiac remodeling to compensatory hypertrophy

Tomoaki Ohtsuka, Mareomi Hamada, Makoto Suzuki, Akiyoshi Ogimoto, Go Hiasa, Osamu Sasaki, Shuntaro Ikeda, Yuji Hara, Yuji Shigematsu, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

50

Comparison of the effect of beta-blocker on natriuretic peptides in patients with dilated cardiomyopathy with atrial fibrillation versus sinus rhythm

Yuji Hara, Mareomi Hamada, Yuji Shigematsu, Makoto Suzuki, Shuntaro Ikeda, Osamu Sasaki, Tomoaki Ohtsuka, Go Hiasa, Akiyoshi Ogimoto, Kunio Hiwada

Journal:

Journal of Cardiac Failure

Year:

1999

Language:

english

File:

PDF, 127 KB

english, 1999